Perimenopause support · By Flore

Support for the shifts of perimenopause.

Metabolism, mood, the intimate microbiome: a lot moves at once. The Radiant One is a multi-strain, single-target formula built on Lactobacillus species studied across the transition, on a flaxseed-lignan matrix your gut converts along the gut-estrogen axis.

  • Multi-strain, one job
  • 26 Billion CFU per capsule
  • One capsule a day, shelf-stable
  • Made in an FDA-registered US facility
The Radiant One30 capsules · 30-day supply · FLOURISH
$49single bottle
One bottle, one time. No subscription required.
Try The Radiant One · $49 →

Checkout opens securely on Shopify. Ships in 2–5 business days. Want more than one? Mix any two for $90 or four for $179.

The Radiant One by GoodOnes
Multi-strain. 1 job.The transition
23,000+microbiome reports analyzed
cGMP facilityFDA-registered, USA
4.5  Flore family · 329 Trustpilot reviews
23,000+  microbiome reports analyzed
18,700+  people served
cGMP  FDA-registered US facility

Why a targeted formula

Your gut has a say in your hormones.

The Radiant One is built for one season of life, and only that.

Built for the transition

Issue-specific Lactobacillus species studied across perimenopause, on the same Universal core that sits in every GoodOne.

Every ingredient on the label

Genus and species printed on the Supplement Facts panel, with the published research on each strain cited per formula. Look any of them up yourself.

Shelf-stable, no fridge

Shelf-stable through the printed expiry date. Gluten-free, non-GMO, no dairy, no soy. Made in an FDA-registered, cGMP-compliant US facility.

What’s inside

Everyday support for a changing system.

L. gasseri has been studied for midlife body composition, stress and sleep; L. fermentum for keeping the vaginal environment Lactobacillus-dominant. They ride on a flaxseed-lignan matrix your own gut bacteria convert along the gut-estrogen axis.

  • Multi-strain, single-target. One job per bottle.
  • 26 Billion CFU per capsule, total.
  • Every ingredient named on the label.
  • No subscription to try it.
Try The Radiant One · $49 →
What’s insideServing size 1 capsule · 30 servings
Issue-specific · the work this bottle is named for
Lactobacillus gasseri†
Lactobacillus fermentum†
Universal core · in every core GoodOne
Bifidobacterium breveThe Anchor†
Lactobacillus plantarumThe Translator†
Lactobacillus rhamnosusThe Regulator†
Prebiotic
Linum usitatissimum (Flaxseed)50 mg
Proprietary probiotic blend, 26 Billion CFU total per capsule. †Daily value not established. Strains listed by genus and species; full designations on file with Flore. One capsule a day with food. Two a day is the maximum across any GoodOnes you stack.

From checkout to day 30

What happens after you order

The research is the backbone. What you feel is the point.

Step 1

Checkout on Shopify

The Radiant One is already in the cart. Orders are typically processed within 2–5 business days and ship USPS or UPS Ground. No cold chain needed.

Step 2

One capsule a day

Take it with a meal. One a day is the sweet spot. Stacking a second GoodOne? Two a day is the maximum.

Step 3

Judge it at day 30

The transition moves on its own timeline. Judge it at day 30, better at day 60. Individual results vary.

Try The Radiant One · $49 →

30-day supply. No subscription required. Checkout opens securely on Shopify.

How it works

Meet the estrobolome.

A set of gut bacteria, sometimes called the estrobolome, helps process estrogen. Lignans from flaxseed are converted by gut bacteria into compounds that work along that same gut-estrogen line.

The Radiant One pairs those lignans with Lactobacillus species studied across the transition, from midlife body composition to the vaginal microbiome.

Does it replace HRT?

No, and it isn’t meant to. Many women use both. Your clinician owns that decision.

What we will and won’t claim

We will say: A 2025 systematic review and meta-analysis of 39 studies and 3,187 women associated probiotics with improved vasomotor and vaginal symptoms during the menopause transition; the authors note the underlying trials carry a high risk of bias, so read it as promising, not proof (PMID 40639456). Those are studies of the strains, not trials of the finished GoodOnes formula. GoodOnes has not run its own randomized controlled trials of the finished formulas.

We will not say: that it replaces HRT or treats any condition. The Radiant One is structure-function support for one body system. Individual results vary.

The Radiant One bottleFLOURISH · The Radiant One

Who makes it

Built by the microbiome scientists at Flore.

GoodOnes is the targeted-formula line from Flore Inc., a microbiome company founded in 2018. The formulas come from what Flore’s microbiome dataset shows, packaged as one job per bottle.

23,000+microbiome reports analyzed
18,700+people served across the Flore family
10 yearsof paired microbiome and outcome data
cGMPFDA-registered US facility. Made in America.

Want a formula built from your own gut data? That’s Flore: a microbiome test, then a formula made from your results.

4.5 out of 5Flore family rating from 329 reviews on TrustpilotRead the reviews →

Is this your One?

The probiotic brand that tells you when not to buy.

A targeted formula only earns its keep if it’s aimed at your actual pattern. Read both columns before you order.

The Radiant One is for you if

  • You’re in your 40s or 50s and your body is changing the rules.
  • Sleep, mood and your midsection all seem to shift at once.
  • You want something to use alongside your clinician’s plan, not instead of it.
  • You want every strain named on the label.

Skip it if

  • You’re pregnant or nursing. Talk to your doctor first.
  • You have symptoms that worry you, like unexpected bleeding or pain. See your clinician.
  • A routine you already use is working. Keep it.
  • You want a treatment. This is a dietary supplement. It is not intended to diagnose, treat, cure, or prevent any disease.

On medication? Keep taking it.

GoodOnes is a supplement. It supports your routine, it doesn’t replace it. The Radiant One is daily nutritional support built to sit alongside whatever your doctor has you on, never instead of it.

Show your doctor the label if you’d like their take.

Questions

Before you order

Can I take it with HRT?

Many women do. It’s a dietary supplement, not a hormone. Show your clinician the label if you’d like their take.

When will I notice anything?

Give it the full 30 days, ideally 60. Individual results vary.

Is it only for perimenopause?

It’s built for the perimenopause transition. If your concern is something else, there’s probably a One built for it. Take the 60-second quiz.

Do I need a subscription?

No. This page sells one bottle for $49, one time. Want two or four? Mix any Ones for $90 a pair or $179 for four on realgoodones.com. Monthly? Subscribe & Save takes 10% off there, and you can cancel before any renewal by emailing support@flore.com.

What is the shipping and return policy?

Orders are typically processed within 2–5 business days and ship USPS or UPS Ground (5–7 business days), with expedited options priced at checkout. All sales are final except for orders that arrive damaged, defective, or incorrect, which Flore replaces or refunds if you email support@flore.com within 14 days of delivery. Full details on the shipping and returns pages.

Who should not take it?

The adult GoodOnes formulas are for ages 18 and over. They are not appropriate for active GI diagnoses that require medical management. If you are pregnant, nursing, have a weakened immune system, or take prescription medication, talk to your doctor before adding any probiotic.

Ready when you are

One bottle. Thirty days. Support for the transition.

No test, no stool sample, no subscription. One targeted formula for perimenopause, every strain on the label. If it isn’t your One, the Flore team will say so.

Try The Radiant One · $49 →

30-day supply. Checkout opens securely on Shopify. Ships in 2–5 business days.

The Radiant One by GoodOnes One capsule a day Built for the transition No subscription Made in the USA

Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results vary. The Radiant One is a general-wellness dietary supplement formulated for adults 18 and over. Strain selection is informed by Flore’s dataset of microbiome reports and by published research on the individual strains; where we describe strain research, we mean published studies on the individual strains, not trials of the finished GoodOnes formula. Consult your healthcare provider before starting any supplement, particularly if you are pregnant, nursing, have a medical condition, or take prescription medication.