Built for GLP-1 users · By Flore

Built for people on a GLP-1 medication.

A GLP-1 medication slows digestion down. The GLP One is a multi-strain, single-target capsule for healthy gut motility and everyday digestive comfort, on a low-viscosity PHGG fiber base.

  • Multi-strain, one job
  • 24 Billion CFU per capsule
  • One capsule a day, shelf-stable
  • Made in an FDA-registered US facility
The GLP One30 capsules · 30-day supply · MOVEMENT
$49single bottle
One bottle, one time. No subscription required.
Try The GLP One · $49 →

Checkout opens securely on Shopify. Ships in 2–5 business days. Want more than one? Mix any two for $90 or four for $179.

The GLP One by GoodOnes
Multi-strain. 1 job.Gut motility
23,000+microbiome reports analyzed
cGMP facilityFDA-registered, USA
4.5  Flore family · 329 Trustpilot reviews
23,000+  microbiome reports analyzed
18,700+  people served
cGMP  FDA-registered US facility

Why a targeted formula

Your medication changed your gut’s pace. Support the pace.

The GLP One skips the shared Universal core. Issue-specific strains on a PHGG fiber base, nothing generic riding along.

No Universal core

Issue-specific strains on a partially hydrolyzed guar gum base, a low-viscosity fiber that doesn’t gel.

Every ingredient on the label

Genus and species printed on the Supplement Facts panel, with the published research on each strain cited per formula. Look any of them up yourself.

Shelf-stable, no fridge

Shelf-stable through the printed expiry date. Gluten-free, non-GMO, no dairy, no soy. Made in an FDA-registered, cGMP-compliant US facility.

What’s inside

Motility and comfort, on a fiber that doesn’t gel.

Bifidobacterium longum and Bacillus coagulans on a partially hydrolyzed guar gum (PHGG) base. Supports healthy gut motility and everyday digestive comfort.

  • Multi-strain, single-target. One job per bottle.
  • 24 Billion CFU per capsule, total.
  • Every ingredient named on the label.
  • No subscription to try it.
Try The GLP One · $49 →
What’s insideServing size 1 capsule · 30 servings
Issue-specific · the work this bottle is named for
Bifidobacterium longum†
Bacillus coagulans†
Prebiotic
Partially hydrolyzed guar gum (Cyamopsis tetragonoloba) (seed)300 mg
Proprietary probiotic blend, 24 Billion CFU total per capsule. †Daily value not established. Strains listed by genus and species; full designations on file with Flore. Estimated pre-launch panel. The final Supplement Facts ship on the bottle and may differ slightly. One capsule a day with food. Two a day is the maximum across any GoodOnes you stack.

From checkout to day 30

What happens after you order

The research is the backbone. What you feel is the point.

Step 1

Checkout on Shopify

The GLP One is already in the cart. Orders are typically processed within 2–5 business days and ship USPS or UPS Ground. No cold chain needed.

Step 2

One capsule a day

One capsule a day with lunch or dinner, with a full glass of water.

Step 3

Judge it at day 30

Judge it across the month, alongside your medication schedule. Individual results vary.

Try The GLP One · $49 →

30-day supply. No subscription required. Checkout opens securely on Shopify.

How it works

Slower digestion is the point of the drug. Comfort is the point of this.

GLP-1 medications slow how fast food leaves the stomach. That’s part of how they work, and it can leave the rest of the gut running slow too.

The GLP One pairs two well-studied species with PHGG, a soluble fiber chosen because it stays thin rather than gelling.

What the evidence covers.

No study has tested these ingredients in people taking a GLP-1 medication. The studies we cite are on the same species in other adults, not on this formula.

What we will and won’t claim

We will say: Bacillus coagulans has been studied for colonic transit time in healthy adults, for example a 2021 randomized controlled trial, n = 80 (PMID 34119240). Those are studies of the strains, not trials of the finished GoodOnes formula. GoodOnes has not run its own randomized controlled trials of the finished formulas.

We will not say: that it treats side effects of your medication or changes how it works. Your prescriber manages your medication. The GLP One is structure-function support for one body system. Individual results vary.

The GLP One bottleMOVEMENT · The GLP One

Who makes it

Built by the microbiome scientists at Flore.

GoodOnes is the targeted-formula line from Flore Inc., a microbiome company founded in 2018. The formulas come from what Flore’s microbiome dataset shows, packaged as one job per bottle.

23,000+microbiome reports analyzed
18,700+people served across the Flore family
10 yearsof paired microbiome and outcome data
cGMPFDA-registered US facility. Made in America.

Want a formula built from your own gut data? That’s Flore: a microbiome test, then a formula made from your results.

4.5 out of 5Flore family rating from 329 reviews on TrustpilotRead the reviews →

Is this your One?

The probiotic brand that tells you when not to buy.

A targeted formula only earns its keep if it’s aimed at your actual pattern. Read both columns before you order.

The GLP One is for you if

  • You take a GLP-1 medication and your gut has slowed down with it.
  • You want support built for that situation, not a generic daily.
  • You want every ingredient named on the label.
  • You’re 18 or over and want to try one bottle first.

Skip it if

  • You have diagnosed gastroparesis, a prior bowel obstruction, or trouble swallowing. Talk to your clinician first.
  • You have severe belly pain, repeated vomiting, or no bowel movement or gas. Stop and get medical care.
  • You aren’t on a GLP-1 medication. The Regular One or The Lean One fits better.
  • You want a treatment. This is a dietary supplement. It is not intended to diagnose, treat, cure, or prevent any disease.

Read this before you order.

On an oral semaglutide pill? Never take this within 30 minutes after it. Take it with lunch or dinner instead.

Diagnosed gastroparesis, a prior bowel obstruction, or trouble swallowing? Talk to your clinician before you start.

Severe belly pain, repeated vomiting, or no bowel movement or gas? Stop and get medical care.

On a prescription? Keep taking it exactly as prescribed, and show your doctor the label if you’d like their take.

Questions

Before you order

When do I take it?

One capsule a day with lunch or dinner, with a full glass of water. On an oral semaglutide pill, never take it within 30 minutes after the pill.

The GLP One or The Lean One?

The Lean One supports your own metabolic signaling. The GLP One is for people already taking a GLP-1 medication.

Why PHGG and not psyllium?

PHGG is a soluble fiber that stays thin rather than gelling, which matters when digestion is already slowed.

Do I need a subscription?

No. This page sells one bottle for $49, one time. Want two or four? Mix any Ones for $90 a pair or $179 for four on realgoodones.com. Monthly? Subscribe & Save takes 10% off there, and you can cancel before any renewal by emailing support@flore.com.

What is the shipping and return policy?

Orders are typically processed within 2–5 business days and ship USPS or UPS Ground (5–7 business days), with expedited options priced at checkout. All sales are final except for orders that arrive damaged, defective, or incorrect, which Flore replaces or refunds if you email support@flore.com within 14 days of delivery. Full details on the shipping and returns pages.

Who should not take it?

The adult GoodOnes formulas are for ages 18 and over. They are not appropriate for active GI diagnoses that require medical management. If you are pregnant, nursing, have a weakened immune system, or take prescription medication, talk to your doctor before adding any probiotic.

Ready when you are

One bottle. Thirty days. Support while your medication does its job.

No test, no stool sample, no subscription. One targeted formula built for GLP-1 users, every ingredient on the label. If it isn’t your One, the Flore team will say so.

Try The GLP One · $49 →

30-day supply. Checkout opens securely on Shopify. Ships in 2–5 business days.

The GLP One by GoodOnes One capsule a day Built for GLP-1 users No subscription Made in the USA

Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results vary. The GLP One is a general-wellness dietary supplement formulated for adults 18 and over. Strain selection is informed by Flore’s dataset of microbiome reports and by published research on the individual strains; where we describe strain research, we mean published studies on the individual strains, not trials of the finished GoodOnes formula. Consult your healthcare provider before starting any supplement, particularly if you are pregnant, nursing, have a medical condition, or take prescription medication.