Built for people on a GLP-1 medication.
A GLP-1 medication slows digestion down. The GLP One is a multi-strain, single-target capsule for healthy gut motility and everyday digestive comfort, on a low-viscosity PHGG fiber base.
- Multi-strain, one job
- 24 Billion CFU per capsule
- One capsule a day, shelf-stable
- Made in an FDA-registered US facility
Checkout opens securely on Shopify. Ships in 2–5 business days. Want more than one? Mix any two for $90 or four for $179.

Why a targeted formula
Your medication changed your gut’s pace. Support the pace.
The GLP One skips the shared Universal core. Issue-specific strains on a PHGG fiber base, nothing generic riding along.
No Universal core
Issue-specific strains on a partially hydrolyzed guar gum base, a low-viscosity fiber that doesn’t gel.
Every ingredient on the label
Genus and species printed on the Supplement Facts panel, with the published research on each strain cited per formula. Look any of them up yourself.
Shelf-stable, no fridge
Shelf-stable through the printed expiry date. Gluten-free, non-GMO, no dairy, no soy. Made in an FDA-registered, cGMP-compliant US facility.
What’s inside
Motility and comfort, on a fiber that doesn’t gel.
Bifidobacterium longum and Bacillus coagulans on a partially hydrolyzed guar gum (PHGG) base. Supports healthy gut motility and everyday digestive comfort.
- Multi-strain, single-target. One job per bottle.
- 24 Billion CFU per capsule, total.
- Every ingredient named on the label.
- No subscription to try it.
| Issue-specific · the work this bottle is named for | |
| Bifidobacterium longum | † |
| Bacillus coagulans | † |
| Prebiotic | |
| Partially hydrolyzed guar gum (Cyamopsis tetragonoloba) (seed) | 300 mg |
From checkout to day 30
What happens after you order
The research is the backbone. What you feel is the point.
Checkout on Shopify
The GLP One is already in the cart. Orders are typically processed within 2–5 business days and ship USPS or UPS Ground. No cold chain needed.
One capsule a day
One capsule a day with lunch or dinner, with a full glass of water.
Judge it at day 30
Judge it across the month, alongside your medication schedule. Individual results vary.
30-day supply. No subscription required. Checkout opens securely on Shopify.
How it works
Slower digestion is the point of the drug. Comfort is the point of this.
GLP-1 medications slow how fast food leaves the stomach. That’s part of how they work, and it can leave the rest of the gut running slow too.
The GLP One pairs two well-studied species with PHGG, a soluble fiber chosen because it stays thin rather than gelling.
What the evidence covers.
No study has tested these ingredients in people taking a GLP-1 medication. The studies we cite are on the same species in other adults, not on this formula.
What we will and won’t claim
We will say: Bacillus coagulans has been studied for colonic transit time in healthy adults, for example a 2021 randomized controlled trial, n = 80 (PMID 34119240). Those are studies of the strains, not trials of the finished GoodOnes formula. GoodOnes has not run its own randomized controlled trials of the finished formulas.
We will not say: that it treats side effects of your medication or changes how it works. Your prescriber manages your medication. The GLP One is structure-function support for one body system. Individual results vary.
MOVEMENT · The GLP OneWho makes it
Built by the microbiome scientists at Flore.
GoodOnes is the targeted-formula line from Flore Inc., a microbiome company founded in 2018. The formulas come from what Flore’s microbiome dataset shows, packaged as one job per bottle.
Want a formula built from your own gut data? That’s Flore: a microbiome test, then a formula made from your results.
Is this your One?
The probiotic brand that tells you when not to buy.
A targeted formula only earns its keep if it’s aimed at your actual pattern. Read both columns before you order.
The GLP One is for you if
- You take a GLP-1 medication and your gut has slowed down with it.
- You want support built for that situation, not a generic daily.
- You want every ingredient named on the label.
- You’re 18 or over and want to try one bottle first.
Skip it if
- You have diagnosed gastroparesis, a prior bowel obstruction, or trouble swallowing. Talk to your clinician first.
- You have severe belly pain, repeated vomiting, or no bowel movement or gas. Stop and get medical care.
- You aren’t on a GLP-1 medication. The Regular One or The Lean One fits better.
- You want a treatment. This is a dietary supplement. It is not intended to diagnose, treat, cure, or prevent any disease.
Read this before you order.
On an oral semaglutide pill? Never take this within 30 minutes after it. Take it with lunch or dinner instead.
Diagnosed gastroparesis, a prior bowel obstruction, or trouble swallowing? Talk to your clinician before you start.
Severe belly pain, repeated vomiting, or no bowel movement or gas? Stop and get medical care.
On a prescription? Keep taking it exactly as prescribed, and show your doctor the label if you’d like their take.
Questions
Before you order
When do I take it?
One capsule a day with lunch or dinner, with a full glass of water. On an oral semaglutide pill, never take it within 30 minutes after the pill.
The GLP One or The Lean One?
The Lean One supports your own metabolic signaling. The GLP One is for people already taking a GLP-1 medication.
Why PHGG and not psyllium?
PHGG is a soluble fiber that stays thin rather than gelling, which matters when digestion is already slowed.
Do I need a subscription?
No. This page sells one bottle for $49, one time. Want two or four? Mix any Ones for $90 a pair or $179 for four on realgoodones.com. Monthly? Subscribe & Save takes 10% off there, and you can cancel before any renewal by emailing support@flore.com.
What is the shipping and return policy?
Orders are typically processed within 2–5 business days and ship USPS or UPS Ground (5–7 business days), with expedited options priced at checkout. All sales are final except for orders that arrive damaged, defective, or incorrect, which Flore replaces or refunds if you email support@flore.com within 14 days of delivery. Full details on the shipping and returns pages.
Who should not take it?
The adult GoodOnes formulas are for ages 18 and over. They are not appropriate for active GI diagnoses that require medical management. If you are pregnant, nursing, have a weakened immune system, or take prescription medication, talk to your doctor before adding any probiotic.
Not your One?
There’s a One for that.
Every GoodOne does one job. Find yours, or take the 60-second quiz.
One bottle. Thirty days. Support while your medication does its job.
No test, no stool sample, no subscription. One targeted formula built for GLP-1 users, every ingredient on the label. If it isn’t your One, the Flore team will say so.
Try The GLP One · $49 →30-day supply. Checkout opens securely on Shopify. Ships in 2–5 business days.
One capsule a day
Built for GLP-1 users
No subscription
Made in the USA