For a gut that runs hot after the wrong meal.
A multi-strain, single-target formula built without tyramine-driving strains, with turmeric and a small amount of melatonin chosen to work with the base. It supports a calmer gut response to trigger foods.
- Multi-strain, one job
- 16 Billion CFU per capsule
- One capsule a day, shelf-stable
- Made in an FDA-registered US facility
Checkout opens securely on Shopify. Ships in 2–5 business days. Want more than one? Mix any two for $90 or four for $179.
Why a targeted formula
Some foods light the fuse. Some bacteria hold the match.
Cool is built around what it leaves out.
Matched to one pattern
Built for the Reactive type: probiotic base, prebiotics and one small modulator. No Universal core in this one.
Every ingredient on the label
Genus and species printed on the Supplement Facts panel, with the published research on each strain cited per formula. Look any of them up yourself.
Shelf-stable, no fridge
Shelf-stable through the printed expiry date. Gluten-free, non-GMO, no dairy, no soy. Made in an FDA-registered, cGMP-compliant US facility.
What’s inside
Built by subtraction.
B. longum, L. plantarum and B. animalis subsp. lactis, with no tyramine-driving strains, fed by green banana fiber and turmeric. A small 2 mg amount of melatonin rounds it out.
- Multi-strain, single-target. One job per bottle.
- 16 Billion CFU per capsule, total.
- Every ingredient named on the label.
- No subscription to try it.
| Phenotype-matched base | |
| Bifidobacterium longum | † |
| Lactiplantibacillus plantarum | † |
| Bifidobacterium animalis subsp. lactis | † |
| Prebiotic | |
| Green banana powder (253 mg) + turmeric (100 mg) | |
| Modulators · small amounts, chosen to work with the base | |
| MelatoninN-acetyl-5-methoxytryptamine | 2 mg |
From checkout to day 30
What happens after you order
The research is the backbone. What you feel is the point.
Checkout on Shopify
Cool is already in the cart. Orders are typically processed within 2–5 business days and ship USPS or UPS Ground. No cold chain needed.
One capsule a day
One capsule a day with your evening meal. It contains 2 mg of melatonin.
Judge it at day 30
Track your reactive days across the month, not one meal. Individual results vary.
30-day supply. No subscription required. Checkout opens securely on Shopify.
How it works
Tyramine adds up.
Tyramine shows up in aged, cured and fermented foods, and some gut bacteria make more of it. For reactive people, that load adds up.
Cool leaves tyramine-driving strains out and feeds the ones it keeps with green banana fiber and turmeric.
Why melatonin?
Your gut makes melatonin too, not just your brain, and it plays a part in the gut lining’s daily rhythm. 2 mg is a small amount, chosen to work with the base. Take it in the evening.
What we will and won’t claim
We will say: The species in Cool have been studied for gut-brain signaling in published research. The citations are listed on the Cool product page. Those are studies of the strains, not trials of the finished GoodOnes formula. GoodOnes has not run its own randomized controlled trials of the finished formulas.
We will not say: that it treats any digestive, headache or other condition, or replaces care from a clinician. Cool is structure-function support for one body system. Individual results vary.
COOL · CoolWho makes it
Built by the microbiome scientists at Flore.
GoodOnes is the targeted-formula line from Flore Inc., a microbiome company founded in 2018. The formulas come from what Flore’s microbiome dataset shows, packaged as one job per bottle.
Want a formula built from your own gut data? That’s Flore: a microbiome test, then a formula made from your results.
Is this your One?
The probiotic brand that tells you when not to buy.
A targeted formula only earns its keep if it’s aimed at your actual pattern. Read both columns before you order.
Cool is for you if
- Certain foods set you off, and your gut lets you know.
- Focus goes foggy after certain meals.
- Your gut runs hot more days than not.
- You’re 18 or over and want to try one bottle first.
Skip it if
- You’re pregnant or nursing. Talk to your doctor first.
- You take blood thinners, sedatives or blood pressure medication and haven’t asked your doctor. This contains turmeric and melatonin.
- You need to be alert right after taking it, like driving. Take it in the evening.
- You want a treatment. This is a dietary supplement. It is not intended to diagnose, treat, cure, or prevent any disease.
Read this before you order.
Contains melatonin (2 mg). Take it in the evening. It may cause drowsiness, so don’t drive or operate machinery after taking it.
Contains turmeric. If you take blood thinners, ask your doctor first.
On a prescription? Keep taking it exactly as prescribed, and show your doctor the label if you’d like their take.
Questions
Before you order
What is the Reactive type?
One of the gut-brain patterns from the 60-second gut-brain quiz: a gut that runs hot and reacts to trigger foods.
When do I take it?
With your evening meal. It contains 2 mg of melatonin, so not before driving.
Cool or Settle?
Cool is for a gut that reacts to trigger foods. Settle is for a sensitive system that reacts all over: gut, skin, everything.
Do I need a subscription?
No. This page sells one bottle for $49, one time. Want two or four? Mix any Ones for $90 a pair or $179 for four on realgoodones.com. Monthly? Subscribe & Save takes 10% off there, and you can cancel before any renewal by emailing support@flore.com.
What is the shipping and return policy?
Orders are typically processed within 2–5 business days and ship USPS or UPS Ground (5–7 business days), with expedited options priced at checkout. All sales are final except for orders that arrive damaged, defective, or incorrect, which Flore replaces or refunds if you email support@flore.com within 14 days of delivery. Full details on the shipping and returns pages.
Who should not take it?
The adult GoodOnes formulas are for ages 18 and over. They are not appropriate for active GI diagnoses that require medical management. If you are pregnant, nursing, have a weakened immune system, or take prescription medication, talk to your doctor before adding any probiotic.
Not your One?
There’s a One for that.
Every GoodOne does one job. Find yours, or take the 60-second quiz.
One bottle. Thirty days. Run a little cooler.
No test, no stool sample, no subscription. One targeted formula for the Reactive pattern, every ingredient on the label. If it isn’t your One, the Flore team will say so.
Try Cool · $49 →30-day supply. Checkout opens securely on Shopify. Ships in 2–5 business days.
One capsule a day
Built for Reactive
No subscription
Made in the USA